On the surface, Victoria Jackson is the American Dream personified: from a troubled childhood and unfinished high school education she overcame immeasurable odds to create a cosmetics empire valued at more than half a billion dollars. Married to Bill Guthy—self-made principal of infomercial marketing giant Guthy-Renker—Victoria's most treasured role was mother to three beautiful, beloved children, Evan, Ali, and Jackson. Suddenly, Victoria's dream life is broken as she begins to battle a mother's greatest fear. In 2008, her daughter, Ali, began experiencing unusual symptoms of blurred vision and an ache in her eye. Her test results led to the diagnosis of a disease so rare, the chance that she had it was only 2%.

Neuromyeltis Optica (NMO) is a little understood, incurable, and often fatal autoimmune disease that can cause blindness, paralysis, and life-threatening seizures, and afflicts as few as 20,000 people in the world. At the age of 14, Ali was given a terrifying prognosis of between four to six years to live. Saving Each Other begins just as Victoria and Bill learn of Al'’s disease, starting them on a powerful journey to save Ali, their only daughter, including bringing together a team of more than fifty of the world's leading experts in autoimmune and NMO-related diseases to create the Guthy-Jackson Charitable Foundation. Told in alternating viewpoints, Victoria and Ali narrate their very different journeys of coming to terms with the lack of control that neither mother nor daughter have over NMO, and their pioneering efforts and courage to take their fight to a global level. Bringing their story to light with raw emotion, humor, warmth, and refreshing candor, Saving Each Other is the extraordinary journey of a mother and daughter who demonstrate how the power of love can transcend our greatest fears, while at the same time battling to find a cure for the incurable.